Overview

The Smiths Medical CADD-Legacy® 1 (Model 6400) is a therapy-specific ambulatory infusion pump engineered for continuous drug delivery. It is part of the CADD-Legacy® family developed by SIMS Deltec — later acquired by Smiths Medical — which established one of the most trusted track records in ambulatory infusion therapy, with CADD® pumps in widespread use since the early 1980s. The 6400 is designed for hospital, outpatient, and home infusion environments, supporting therapies including antibiotic administration, hydration, chemotherapy, palliative care, and continuous pain management — anywhere a reliable, steady infusion rate is required over an extended treatment period. Smiths Medical discontinued sale of the CADD-Legacy® pump line effective December 31, 2022, but these pumps remain in widespread clinical use across home infusion, oncology, and specialty pharmacy settings, and IPR Medical fully supports the platform through sales, repair, and parts availability.

Delivery and Programming

The CADD-Legacy® 1 operates in continuous delivery mode, with rates programmable from 1 to 3,000 ml per day — equivalent to approximately 0.04 to 125 ml/hr — in 1 ml/day increments. Uniquely among the CADD-Legacy® family, the 6400 programs and displays its rate in ml/24 hours rather than ml/hr, which aligns with the established convention in many home infusion and pain management protocols. System delivery accuracy is ±6% (nominal), which averages out over the total infusion time; the OEM manual recommends accounting for this tolerance when programming rates and filling reservoirs to ensure medication is not depleted earlier than anticipated. The pump uses three programmable security lock levels (LL0 through LL2) to prevent unauthorized patient access to clinical programming. Reservoir volume is tracked continuously and displayed in 0.1 ml increments, with a low-reservoir alarm alerting the clinician when the cassette is running low. The event memory retains the last 1,000 pump events, which can be downloaded directly or via remote modem to a PC using the CADD-DIPLOMAT® PC Communications System for clinical review and compliance documentation.

Safety and Alarm Features

The CADD-Legacy® 1 incorporates a comprehensive safety architecture. Upstream and downstream occlusion sensors monitor both the supply-side and patient-side of the fluid path, stopping delivery and triggering audible and visual alarms if a blockage is detected on either side. An air-in-line detector with three adjustable sensitivity settings — Off, Low, and High — halts the pump immediately if air is detected in the tubing. A cassette detection sensor confirms proper reservoir attachment before and during operation, alerting the clinician if the cassette is missing, unseated, or damaged. Battery status is monitored continuously, with separate low-battery and battery-depleted alarms to prevent therapy interruptions due to power loss. The complete alarm list covers 14 distinct fault conditions, including motor lock, key-stuck, and disposable-detached events, ensuring rapid identification of any system problem during operation.

Portability and Power

Weighing just 0.86 lbs with batteries and empty reservoir installed, the CADD-Legacy® 1 is one of the lightest ambulatory pumps available. It is designed to fit inside the included single-use 50 ml or 100 ml pump pouch for discreet ambulatory carry. Two AA alkaline batteries serve as the primary power source, delivering approximately 15 hours of runtime at the maximum rate of 125 ml/hr, or up to approximately 14 days at low-rate ambulatory protocols of 10 ml/day — a critical specification for home infusion patients. An optional AC adapter is available for stationary or bedside use, with the batteries remaining installed as a backup during AC operation. A threaded mounting hole on the rear panel of the pump allows attachment to a pole-mount bracket adapter for IV stand or bedside rail use in clinical settings. The ON/OFF key places the pump in a low-power standby state to conserve battery life during storage or transport between therapy sessions.

Compatible Administration Sets and Consumables

The CADD-Legacy® 1 is compatible with CADD® Medication Cassette Reservoirs in 50 ml, 100 ml, and 250 ml sizes, which attach directly to the bottom of the pump. For therapies requiring larger fluid volumes, CADD® Administration Sets connect to an external fluid container of the clinician’s choice. CADD® extension sets with integral anti-siphon valves are required to protect against unregulated gravity infusion if the cassette is removed or not properly seated. IPR Medical stocks CADD-compatible administration sets and reservoirs for this pump family, providing a single-source solution for facilities that need both the pump platform and its consumables — eliminating the need to source infusion sets separately.

FDA Device Corrections and Safety Bulletins

In December 2022, Smiths Medical issued an Urgent Medical Device Correction Letter — classified by the FDA as a Class I recall — affecting CADD Administration Sets and CADD Medication Cassette Reservoirs used with all CADD infusion pumps, including the CADD-Legacy® 1 (Model 6400). The correction addresses two distinct issues with affected consumables. The first issue involves potential tubing occlusion: manufacturing variations in the green CADD Flow Stop arm may cause it to partially compress and block the fluid path before clinical use. If the occlusion does not resolve when the reservoir or set is connected to the pump, the pump may not detect it — meaning the pump display may indicate that the infusion is running normally while medication is not being delivered or is being under-delivered. The second issue involves false “No Disposable Attached” (NDA) alarms, which is specific to CADD-Legacy® pumps. Manufacturing variations in certain 50 ml and 700 ml CADD Medication Cassette Reservoirs with Flow Stop may prevent the pump from detecting a properly attached cassette, triggering an NDA alarm that interrupts therapy. This issue does not affect 250 ml Flow Stop or non-Flow Stop reservoirs.

Recommended actions for CADD-Legacy® 1 users: When priming, watch fluid flow carefully — if fluid does not flow properly, takes an abnormally long time, or the pump shows a higher-than-expected priming volume, replace the reservoir or administration set immediately. If an NDA alarm occurs with a 50 ml or 700 ml Flow Stop reservoir, attempt to reposition or reattach the cassette, or replace it. For patients on life-sustaining medications, contact your specialty pharmacy to discuss availability of alternative CADD infusion sets. Pumps and sets themselves do not need to be returned.

Because FDA device corrections and safety communications may be updated or expanded after the date of this listing, IPR Medical recommends that facilities also check the FDA’s official resources directly to ensure they have the most current information:

• • FDA Medical Device Recalls Database
  • FDA Medical Device Safety

IPR Medical — Sales, Repair, and Parts

IPR Medical buys, sells, repairs, and stocks parts and administration sets for the Smiths Medical CADD-Legacy® 1 (Model 6400). Although Smiths Medical discontinued sale of this pump line in December 2022, these pumps remain in active clinical use and IPR Medical is fully equipped to support facilities running this platform. Our biomedical technicians are experienced with the complete CADD-Legacy® family and can service, test, and return units to clinical readiness. We also stock CADD-compatible administration sets and reservoirs, making IPR Medical a single-source resource for both the pump and its consumables. Contact us to discuss availability, fleet repair programs, or trade-in options.

IPR Medical buys, sells, repairs, and stocks parts and administration sets for the Smiths Medical CADD-Legacy® 1 (Model 6400). Contact us at 855-477-8866 or cs@iprmed.com.